Thiourea-catalyzed aminolysis of N-acyl homoserine lactones.
نویسندگان
چکیده
Thiourea catalysts accelerate aminolysis of N-acyl homoserine lactones (AHLs), molecules integral to bacterial quorum sensing. The catalysts afford rate enhancement of up to 10 times the control in CD(3)CN. Mild catalysis in other polar aprotic solvents is still observed, while the activity is attenuated in polar protic solvents.
منابع مشابه
Thermoregulation of N-acyl homoserine lactone-based quorum sensing in the soft rot bacterium Pectobacterium atrosepticum.
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 20 شماره
صفحات -
تاریخ انتشار 2013